CISAC has five regional committees, each in charge of representing the specific issues within their geographical area. The five regional committees comprise:
- Regional African Committee (CAF)
- Regional Asia-Pacific Committee (CAP)
- Regional Canada/USA Committee (CCU)
- Regional European Committee (EC)
- Regional Latin American and Caribbean Committee (CLC)
Each regional committee forms a statutory advisory body to promote the interests of the creative community and its intellectual property in their specific region.
Among their priorities, regional committees are responsible for:
- Coordinating CISAC activities in the region through promoting the enactment of legislation
- Assisting in the establishment of necessary administrative infrastructures for the creation and effective operation of societies in those countries within the territory where no collective management organisations exist
- Providing encouragement and assistance for developing and strengthening member societies in those countries where such collective management organisations exist but are not fully-effective
- Nurturing constructive relations and cooperation between societies
- Addressing and studying issues and problems directly linked to the moral, material and professional interests of creators and member societies within the territory
- Fulfilling all other functions that contribute to the development of member societies
- Determining its own working rules.